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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAGE
All Species:
11.82
Human Site:
S392
Identified Species:
23.64
UniProt:
Q9UQ07
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ07
NP_055041.1
419
48014
S392
P
L
K
C
I
P
A
S
K
K
T
D
P
Q
K
Chimpanzee
Pan troglodytes
XP_510176
419
47983
S392
P
L
K
C
I
P
A
S
K
K
T
D
P
R
K
Rhesus Macaque
Macaca mulatta
XP_001112517
461
52662
T433
P
L
K
C
I
P
A
T
K
K
T
D
P
R
K
Dog
Lupus familis
XP_547985
458
51843
N432
P
L
K
C
V
G
A
N
Q
K
T
D
A
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVS4
420
48046
N392
P
L
K
C
A
A
V
N
K
K
T
D
T
Q
K
Rat
Rattus norvegicus
Q62726
629
70550
G501
P
G
I
N
I
R
N
G
V
L
P
N
P
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
K279
P
A
K
R
I
S
G
K
M
A
L
N
H
P
Y
Frog
Xenopus laevis
NP_001084801
411
47114
T387
Y
F
E
T
K
V
N
T
T
T
L
N
P
F
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23573
314
35870
V290
Q
H
A
Y
F
R
N
V
Q
H
V
D
H
V
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786078
440
50923
N406
S
I
A
N
T
H
Y
N
K
H
H
H
T
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43294
443
50877
T416
P
P
Q
S
S
G
F
T
M
T
S
S
M
Q
P
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
K274
R
G
I
D
L
L
D
K
L
L
A
Y
D
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
82.6
76.6
N.A.
83.5
27.8
N.A.
N.A.
28.6
63.2
N.A.
N.A.
26.7
N.A.
N.A.
50.6
Protein Similarity:
100
99.5
85.2
81.2
N.A.
89.5
42.4
N.A.
N.A.
43.9
73.2
N.A.
N.A.
42.7
N.A.
N.A.
68.4
P-Site Identity:
100
93.3
86.6
66.6
N.A.
66.6
26.6
N.A.
N.A.
20
6.6
N.A.
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
33.3
N.A.
N.A.
26.6
26.6
N.A.
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
28.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.6
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
0
9
9
34
0
0
9
9
0
9
0
9
% A
% Cys:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
9
0
0
0
0
50
9
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
9
0
9
0
0
0
0
0
0
9
9
% F
% Gly:
0
17
0
0
0
17
9
9
0
0
0
0
0
9
0
% G
% His:
0
9
0
0
0
9
0
0
0
17
9
9
17
0
0
% H
% Ile:
0
9
17
0
42
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
50
0
9
0
0
17
42
42
0
0
0
0
59
% K
% Leu:
0
42
0
0
9
9
0
0
9
17
17
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
17
0
0
0
9
0
0
% M
% Asn:
0
0
0
17
0
0
25
25
0
0
0
25
0
0
0
% N
% Pro:
67
9
0
0
0
25
0
0
0
0
9
0
42
17
9
% P
% Gln:
9
0
9
0
0
0
0
0
17
0
0
0
0
34
0
% Q
% Arg:
9
0
0
9
0
17
0
0
0
0
0
0
0
17
0
% R
% Ser:
9
0
0
9
9
9
0
17
0
0
9
9
0
0
0
% S
% Thr:
0
0
0
9
9
0
0
25
9
17
42
0
17
9
0
% T
% Val:
0
0
0
0
9
9
9
9
9
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
9
0
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _